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Clin Gastroenterol Hepatol. 2014 Jul;12(7):1077-84; quiz e59-60. doi: 10.1016/j.cgh.2013.08.014. Epub 2013 Aug 17.

Management of dyslipidemia as a cardiovascular risk factor in individuals with nonalcoholic fatty liver disease.

Author information

1
Department of Medicine, Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts.
2
Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana. Electronic address: nchalasa@iupui.edu.

Abstract

Nonalcoholic fatty liver disease (NAFLD) is the most frequent cause of liver disease in the United States and is associated with an increased risk of cardiovascular disease (CVD) and cardiovascular (CV) mortality, independent of traditional cardiovascular risk factors. CVD is one of the most common causes of death among individuals with NAFLD and management of NAFLD must extend beyond liver disease to include CVD risk modification. Clinicians should assess CVD risk with the Framingham Risk Score and screen for CVD risk factors including dyslipidemia, diabetes mellitus, hypertension, tobacco use, and the metabolic syndrome. CVD risk factors, particularly dyslipidemia, require aggressive medical management to reduce the high risk of CVD events and death in individuals with NAFLD.

KEYWORDS:

Cardiovascular Disease; Dyslipidemia; Nonalcoholic Fatty Liver Disease

PMID:
23962548
PMCID:
PMC3933450
DOI:
10.1016/j.cgh.2013.08.014
[Indexed for MEDLINE]
Free PMC Article

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