Format

Send to

Choose Destination
See comment in PubMed Commons below
Z Med Phys. 2014 Mar;24(1):55-64. doi: 10.1016/j.zemedi.2013.07.005. Epub 2013 Aug 17.

MRI compatible small animal monitoring and trigger system for whole body scanners.

Author information

1
Medical Physics Group, Institute for Diagnostic and Interventional Radiology I, Jena University Hospital, Philosophenweg 3, Gebäude 5, 07743 Jena, Germany. Electronic address: karl-heinz.herrmann@med.uni-jena.de.
2
Medical Physics Group, Institute for Diagnostic and Interventional Radiology I, Jena University Hospital, Philosophenweg 3, Gebäude 5, 07743 Jena, Germany; Ernst-Abbe-Fachhochschule Jena, Carl-Zeiss-Promenade 2, 07745 Jena, Germany.
3
Medical Physics Group, Institute for Diagnostic and Interventional Radiology I, Jena University Hospital, Philosophenweg 3, Gebäude 5, 07743 Jena, Germany.
4
Ernst-Abbe-Fachhochschule Jena, Carl-Zeiss-Promenade 2, 07745 Jena, Germany.

Abstract

Performing magnetic resonance imaging (MRI) experiments with small animals requires continuous monitoring of vital parameters, especially the respiration rate. Clinical whole-body MR scanners represent an attractive option for preclinical imaging as dedicated animal scanners are cost-intensive in both investment and maintenance, thus limiting their availability. Even though impressive image quality is achievable with clinical MR systems in combination with special coils, their built-in physiologic monitoring and triggering units are often not suited for small animal imaging. In this work, we present a simple, MRI compatible low cost solution to monitor the respiration and heart rate of small animals in a clinical whole-body MR scanner. The recording and processing of the biosignals as well as the optimisation of the respiratory trigger generation is decribed. Additionally rat and mouse in-vivo MRI experiments are presented to illustrate the effectiveness of the monitoring and respiratory trigger system in suppressing motion artifacts.

KEYWORDS:

Atemtriggerung; Bewegungsunterdrückung; Kleintierbildgebung; MRI; MRT; Small animal imaging; motion suppression; physiological monitoring; physiologische Überwachung; respiratory trigger

PMID:
23962379
DOI:
10.1016/j.zemedi.2013.07.005
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center