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Chem Commun (Camb). 2013 Oct 7;49(77):8716-8. doi: 10.1039/c3cc44188a.

Single-molecule photon-fueled DNA nanoscissors for DNA cleavage based on the regulation of substrate binding affinity by azobenzene.

Author information

1
The Key Laboratory of Analytical Science, Key Laboratory for Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China. cyyang@xmu.edu.cn.

Abstract

A pair of single-molecule photo-responsive DNA nanoscissors for DNA cleavage based on the regulation of substrate binding affinity was designed and fabricated. Compared with other DNA nanomachines, our DNA nanoscissors have the advantages of a clean switching mechanism, as well as robust and highly reversible operation.

PMID:
23958857
DOI:
10.1039/c3cc44188a
[Indexed for MEDLINE]

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