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Cell Res. 2013 Oct;23(10):1161-2. doi: 10.1038/cr.2013.111. Epub 2013 Aug 20.

The years of the monkey.

Author information

1
Departments of Cell and Molecular Biology and Medicine, Karolinska Institutet, Stockholm, Sweden.

Abstract

The fact that mammals are diploid sets a barrier to rapidly understand the function of non-coding and coding genes in the genome. Recently, Yang et al. reported successful derivation of monkey haploid embryonic stem cells from parthenotes, which provide an effective platform for studying mammalian gene function and enable reverse genetic screening of genes for recessive phenotypes in monkeys.

PMID:
23958583
PMCID:
PMC3790233
DOI:
10.1038/cr.2013.111
[Indexed for MEDLINE]
Free PMC Article

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