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Lab Chip. 2013 Oct 7;13(19):3956-64. doi: 10.1039/c3lc50558h.

Clear castable polyurethane elastomer for fabrication of microfluidic devices.

Author information

1
Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA 02115, USA. don.ingber@wyss.harvard.edu.

Abstract

Polydimethylsiloxane (PDMS) has numerous desirable properties for fabricating microfluidic devices, including optical transparency, flexibility, biocompatibility, and fabrication by casting; however, partitioning of small hydrophobic molecules into the bulk of PDMS hinders industrial acceptance of PDMS microfluidic devices for chemical processing and drug development applications. Here we describe an attractive alternative material that is similar to PDMS in terms of optical transparency, flexibility and castability, but that is also resistant to absorption of small hydrophobic molecules.

PMID:
23954953
PMCID:
PMC3877836
DOI:
10.1039/c3lc50558h
[Indexed for MEDLINE]
Free PMC Article
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