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Fertil Steril. 2013 Nov;100(5):1289-95. doi: 10.1016/j.fertnstert.2013.07.1966. Epub 2013 Aug 15.

Thin endometrium in donor oocyte recipients: enigma or obstacle for implantation?

Author information

1
Division of Fertility-In Vitro Fertilization, Department of Obstetrics and Gynecology, Carmel Medical Center, Faculty of Medicine, Technion, Haifa, Israel.

Abstract

OBJECTIVE:

To evaluate the combined effect of endometrial thickness and anatomic uterine factors on clinical outcome in oocyte donation recipients.

DESIGN:

Retrospective analysis of oocyte donation cycles conducted between 2005 and 2010.

SETTING:

Two private IVF centers.

PATIENT(S):

A total of 737 donor oocyte cycles.

INTERVENTION(S):

None.

MAIN OUTCOME MEASURE(S):

Clinical pregnancy and live birth rates.

RESULT(S):

No statistically significant difference was found in clinical pregnancy rates and live birth rates in cycles with endometrial thickness <6 mm compared with those with endometrial thickness >10 mm. However, a relatively high rate of live births was found within a medium range of endometrial thickness (8.2-10 mm). All intrauterine adhesion cases occurred in cycles with thinner endometrium.

CONCLUSION(S):

No statistically significant difference was found in clinical pregnancy rates and live birth rates in cycles with endometrial thickness <6 mm compared with those with thickness >6 mm. A relatively high rate of live births was found within a medium range of endometrial thickness (9.1-10 mm).

KEYWORDS:

Endometrial thickness; estrogen replacement therapy; oocyte donation; uterine factors

[Indexed for MEDLINE]

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