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J Clin Neurosci. 2014 Feb;21(2):354-5. doi: 10.1016/j.jocn.2013.03.021. Epub 2013 Aug 15.

Restless legs syndrome and akathisia as manifestations of acute pontine infarction.

Author information

1
Department of Neurology, Chung-Ang University College of Medicine, 224-1, Heukseok-dong, Dongjak-gu, Seoul 156-755, South Korea.
2
Department of Neurology, Chung-Ang University College of Medicine, 224-1, Heukseok-dong, Dongjak-gu, Seoul 156-755, South Korea. Electronic address: shinhw@cau.ac.kr.

Abstract

Although restless legs syndrome (RLS) and akathisia have similar clinical manifestations and seem to share a common pathophysiology, they are regarded as distinct clinical syndromes. We present three patients with acute pontine infarction and RLS or akathisia as clinical manifestations. They presented with abrupt onset of restlessness of various body parts, as well as other neurological signs including dysarthria or weakness of the legs. Brain MRI of all three patients showed acute pontine infarction. The clinical syndrome in two of the patients was compatible with RLS and one with akathisia. Their symptoms improved after a brief period. Our finding of secondary RLS and akathisia as manifestations of acute pontine infarction provides information that assists in understanding the common anatomical and pathophysiological basis of RLS and akathisia.

KEYWORDS:

Akathisia; Pontine infarction; Restless legs syndrome

PMID:
23953640
DOI:
10.1016/j.jocn.2013.03.021
[Indexed for MEDLINE]
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