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Reprod Biomed Online. 2013 Oct;27(4):338-52. doi: 10.1016/j.rbmo.2013.06.011. Epub 2013 Jun 28.

Twelve years of MSOME and IMSI: a review.

Author information

1
Sapientiae Institute - Centro de Estudos e Pesquisa em Reprodução Humana Assistida, Rua Vieira Maciel, 62, São Paulo, SP 04503-040, Brazil; Fertility - Centro de Fertilização Assistida, Av. Brigadeiro Luis Antonio, 4545, São Paulo, SP 01401-002, Brazil.

Abstract

A promising method for observing spermatozoa, motile sperm organelle morphology examination (MSOME) enables the evaluation of the nuclear morphology of motile spermatozoa in real time at high magnification and has allowed the introduction of a modified microinjection procedure, intracytoplasmic morphologically selected sperm injection (IMSI). Since its development, several studies have intensively investigated the efficacy of MSOME and IMSI. The objective of the present study is to review the current literature on the MSOME and IMSI techniques. A promising method for observing spermatozoa, motile sperm organelle morphology examination (MSOME), enables the evaluation of the nuclear morphology of motile spermatozoa in real time at high magnification and has allowed the introduction of a modified microinjection procedure, intracytoplasmic morphologically selected sperm injection (IMSI). Since its development, several studies have intensively investigated the efficacy of MSOME and IMSI. The objective of the present study is to review the current literature on the MSOME and IMSI techniques.

KEYWORDS:

ICSI; IMSI; MSOME; sperm morphology

PMID:
23948449
DOI:
10.1016/j.rbmo.2013.06.011
[Indexed for MEDLINE]

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