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Cancer Cell. 2013 Aug 12;24(2):145-7. doi: 10.1016/j.ccr.2013.07.018.

IL-11: a prominent pro-tumorigenic member of the IL-6 family.

Author information

1
Cancer Prevention and Control Program, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111-2497, USA. sergey.grivennikov@fccc.edu

Abstract

Cytokines have recently emerged as important players in tumor promotion and progression. In this issue of Cancer Cell, Putoczki and colleagues report the importance of interleukin 11 in a variety of gastrointestinal malignances and lay down a framework for its potential inhibition in a variety of human cancers.

PMID:
23948295
PMCID:
PMC3855069
DOI:
10.1016/j.ccr.2013.07.018
[Indexed for MEDLINE]
Free PMC Article

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