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Clin Infect Dis. 2013 Nov;57(10):1458-60. doi: 10.1093/cid/cit542. Epub 2013 Aug 13.

Impact of colonization pressure and strain type on methicillin-resistant Staphylococcus aureus transmission in children.

Author information

1
Division of Pediatric Infectious Diseases, Department of Pediatrics.

Abstract

We studied the transmissibility of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) and healthcare-associated methicillin-resistant S. aureus (HA-MRSA) strains and the association of MRSA colonization pressure and MRSA transmission in critically ill children. Importantly, we found that in hospitalized children MRSA colonization pressure above 10% increases the risk of MRSA transmission 3-fold, and CA-MRSA and HA-MRSA strains have similar transmission dynamics.

KEYWORDS:

colonization pressure; healthcare-associated infections; intensive care unit; methicillin-resistant Staphylococcus aureus; transmission

PMID:
23943821
PMCID:
PMC3805173
DOI:
10.1093/cid/cit542
[Indexed for MEDLINE]
Free PMC Article

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