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Clin Appl Thromb Hemost. 2014 Sep;20(6):577-82. doi: 10.1177/1076029613500707. Epub 2013 Aug 12.

Relationship Between Red Cell Distribution Width and the GRACE Risk Score With In-Hospital Death in Patients With Acute Coronary Syndrome.

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Department of Cardiology, Faculty of Medicine, Dicle University, Diyarbakir, Turkey
Department of Cardiology, Faculty of Medicine, Dicle University, Diyarbakir, Turkey.


The aim of this study was to evaluate the relationship between red cell distribution width (RDW) and Global Registry of Acute Coronary Events (GRACE) risk score in patients with unstable angina pectoris (UAP) and non-ST elevation myocardial infarction (NSTEMI). We retrospectively enrolled 193 patients with UAP/NSTEMI (mean age 63.6 ± 12.6 years; men 57%) in this study. Higher RDW values were associated with increased in-hospital mortality (P = .001). There is a significant correlation between RDW and GRACE score (P < .001). In multivariate logistic regression analysis, RDW was found to be an independent predictor of high GRACE score (odds ratio: 1.513, 95% confidence interval: 1.116-2.051, P = .008). A cutoff value of >15.74 for RDW predicted high GRACE score, with a 64% sensitivity and 65% specificity. Our study results demonstrated that high RDW was an independent predictor of high GRACE score, and it is associated with in-hospital mortality in UAP/NSTEMI.


GRACE; cardiovascular mortality; non-ST elevation myocardial infarction; red blood cell distribution width; unstable angina pectoris

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