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Nat Rev Mol Cell Biol. 2013 Sep;14(9):592-9. doi: 10.1038/nrm3641. Epub 2013 Aug 14.

Protein adaptation: mitotic functions for membrane trafficking proteins.

Author information

1
Division of Biomedical Cell Biology, Warwick Medical School, Gibbet Hill Road, Coventry, CV4 7AL, UK. s.j.royle@warwick.ac.uk

Abstract

Membrane trafficking and mitosis are two essential processes in eukaryotic cells. Surprisingly, many proteins best known for their role in membrane trafficking have additional 'moonlighting' functions in mitosis. Despite having proteins in common, there is insufficient evidence for a specific connection between these two processes. Instead, these phenomena demonstrate the adaptability of the membrane trafficking machinery that allows its repurposing for different cellular functions.

PMID:
23942451
DOI:
10.1038/nrm3641
[Indexed for MEDLINE]

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