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Mar Drugs. 2013 Aug 12;11(8):2846-72. doi: 10.3390/md11082846.

Diversity of secondary metabolites from marine Bacillus species: chemistry and biological activity.

Author information

1
School of Science and Technology, Bangladesh Open University, Board Bazar, Gazipur 1705, Bangladesh. mondol_sst@yahoo.com

Abstract

Marine Bacillus species produce versatile secondary metabolites including lipopeptides, polypeptides, macrolactones, fatty acids, polyketides, and isocoumarins. These structurally diverse compounds exhibit a wide range of biological activities, such as antimicrobial, anticancer, and antialgal activities. Some marine Bacillus strains can detoxify heavy metals through reduction processes and have the ability to produce carotenoids. The present article reviews the chemistry and biological activities of secondary metabolites from marine isolates. Side by side, the potential for application of these novel natural products from marine Bacillus strains as drugs, pesticides, carotenoids, and tools for the bioremediation of heavy metal toxicity are also discussed.

PMID:
23941823
PMCID:
PMC3766869
DOI:
10.3390/md11082846
[Indexed for MEDLINE]
Free PMC Article

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