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AIDS. 2013 Sep 24;27(15):2488-91. doi: 10.1097/01.aids.0000432443.22684.50.

Evidence for continuing cross-species transmission of SIVsmm to humans: characterization of a new HIV-2 lineage in rural Côte d'Ivoire.

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aUMI 233, IRD and University of Montpellier 1, Montpellier, France bDepartment of Diagnostics, Teaching Hospital, University of Bouake, Côte d'Ivoire cProject group Epidemiology of Highly Pathogenic Microorganisms RKI, Berlin, Germany dDepartment of Microbiology and Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.


HIV types 1 and 2 (HIV-1 and HIV-2) are the result of multiple cross-species transmissions of their simian counterparts (SIVs) to humans. We studied whether new SIVs lineages have been transmitted to humans in rural Côte d'Ivoire and identified a novel HIV-2 variant (HIV-2-07IC-TNP03) not related to any of the previously defined HIV-2 groups. This finding shows that sooty mangabey viruses continue to be transmitted to humans, causing new zoonotic outbreaks.

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