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J Obstet Gynaecol Res. 2014 Jan;40(1):255-8. doi: 10.1111/jog.12129. Epub 2013 Aug 12.

Vulvar pseudoepitheliomatous hyperplasia associated with herpes simplex virus type II mimicking cancer in an immunocompromised patient.

Author information

1
Department of Obstetrics and Gynecology, University of Bangkok Metropolis, Bangkok, Thailand.

Abstract

We report an exaggerated dermatological inflammatory condition in an immunocompromised patient. The patient was a 51-year-old woman who had HIV infection and a history of cervical cancer. Three years after highly active antiretroviral therapy with an improved immune status, and 2 years after remission of cervical cancer, she developed verrucous perineal masses. Provisional diagnosis was recurrent cervical cancer or primary vulvar cancer. Pathological features revealed pseudoepitheliomatous hyperplasia associated with herpes viral infection. After minimal response to systemic oral antiviral drugs and topical imiquimod, she had clinical resolution with the addition of systemic oral corticosteroid.

KEYWORDS:

herpes simplex virus; immunocompromised; vulvar pseudoepitheliomatous hyperplasia

PMID:
23937292
DOI:
10.1111/jog.12129
[Indexed for MEDLINE]
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