Dearomatizing conjugate addition to quinolinyl amidines for the synthesis of dehaloperophoramidine through tandem arylation and allylation

Angew Chem Int Ed Engl. 2013 Sep 23;52(39):10204-7. doi: 10.1002/anie.201305581. Epub 2013 Aug 9.

Authors

Takayuki Ishida¹, Hideo Ikota, Kei Kurahashi, Chihiro Tsukano, Yoshiji Takemoto

Affiliation

¹ Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto, 606-8501 (Japan).

PMID: 23934788
DOI: 10.1002/anie.201305581

No abstract available

Keywords: allylation; amidine; dearomatization; natural products; perophoramidine.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Allyl Compounds / chemistry
Amidines / chemical synthesis
Amidines / chemistry*
Aminoquinolines / chemistry*
Biological Products / chemical synthesis*
Biological Products / chemistry
Heterocyclic Compounds, 4 or More Rings / chemical synthesis*
Heterocyclic Compounds, 4 or More Rings / chemistry
Hydrocarbons, Halogenated / chemical synthesis*
Hydrocarbons, Halogenated / chemistry
Stereoisomerism

Substances

Allyl Compounds
Amidines
Aminoquinolines
Biological Products
Heterocyclic Compounds, 4 or More Rings
Hydrocarbons, Halogenated
perophoramidine