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J Invertebr Pathol. 2013 Oct;114(2):186-95. doi: 10.1016/j.jip.2013.07.006. Epub 2013 Aug 8.

Arthropod viruses and small RNAs.

Author information

1
Department of Entomology, Iowa State University, Ames, IA 50011, USA.

Abstract

The recently characterized small RNAs provide a new paradigm for physiological studies. These molecules have been shown to be integral players in processes as diverse as development and innate immunity against bacteria and viruses in eukaryotes. Several of the well-characterized small RNAs including small interfering RNAs, microRNAs and PIWI-interacting RNAs are emerging as important players in mediating arthropod host-virus interactions. Understanding the role of small RNAs in arthropod host-virus molecular interactions will facilitate manipulation of these pathways for both management of arthropod pests of agricultural and medical importance, and for protection of beneficial arthropods such as honey bees and shrimp. This review highlights recent research on the role of small RNAs in arthropod host-virus interactions with reference to other host-pathogen systems.

KEYWORDS:

Antiviral immunity; MicroRNA; PIWI-associated RNA; Small interfering RNA; VSR; unusually small RNA (13–19nt); usRNA; viral suppressor of RNAi; virus-derived small interfering RNA; vsRNA

PMID:
23932976
DOI:
10.1016/j.jip.2013.07.006
[Indexed for MEDLINE]

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