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Am J Infect Control. 2013 Nov;41(11):1116-8. doi: 10.1016/j.ajic.2013.04.017. Epub 2013 Aug 7.

Inappropriate use of antibiotics and Clostridium difficile infection.

Author information

1
Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada; Infection Prevention and Control, University Health Network, Toronto, ON, Canada; University of Toronto, Toronto, ON, Canada.

Abstract

We assessed appropriateness of preceding and concurrent antibiotics in 126 consecutive patients with hospital-associated Clostridium difficile infection. In 93 (73.8%) episodes, at least 1 preceding course of antibiotics was inappropriate. We provided feedback on concurrent antibiotics on the day of diagnosis during the final 8 months: 17 of 74 (23.0%) patients were on inappropriate antibiotics. Our recommendations were well received. Reviewing C difficile-infected patients allowed for identification of opportunities to improve antibiotic utilization and potentially improved patient outcomes.

KEYWORDS:

Antimicrobial stewardship; Health care-associated infection; Quality improvement

PMID:
23932828
DOI:
10.1016/j.ajic.2013.04.017
[Indexed for MEDLINE]
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