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Singapore Med J. 1990 Jun;31(3):286-8.

Disseminated histoplasmosis presenting as a non-healing tongue ulcer.

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Department of Medicine, University Hospital, Faculty of Medicine, University of Malaya, Kuala Lumpur.


A 51-year old man presented with a persistent tongue ulcer, fever, cervical lymphadenopathy and hepatomegaly. The diagnosis was initially thought to be tuberculosis. This led to the initiation of antituberculous chemotherapy to which the patient failed to respond. The correct diagnosis of histoplasmosis was made after the detection of Histoplasma capsulatum on further review of the tongue ulcer biopsy specimen. He responded to treatment with amphotericin B.

[Indexed for MEDLINE]

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