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J Virol. 2013 Oct;87(20):11292-9. doi: 10.1128/JVI.01643-13. Epub 2013 Aug 7.

Transient compartmentalization of simian immunodeficiency virus variants in the breast milk of african green monkeys.

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1
Human Vaccine Institute.

Abstract

Natural hosts of simian immunodeficiency virus (SIV), African green monkeys (AGMs), rarely transmit SIV via breast-feeding. In order to examine the genetic diversity of breast milk SIV variants in this limited-transmission setting, we performed phylogenetic analysis on envelope sequences of milk and plasma SIV variants of AGMs. Low-diversity milk virus populations were compartmentalized from that in plasma. However, this compartmentalization was transient, as the milk virus lineages did not persist longitudinally.

PMID:
23926337
PMCID:
PMC3807282
DOI:
10.1128/JVI.01643-13
[Indexed for MEDLINE]
Free PMC Article
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