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Infect Control Hosp Epidemiol. 2013 Sep;34(9):990-5. doi: 10.1086/671731. Epub 2013 Jul 25.

Can matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF) enhance antimicrobial stewardship efforts in the acute care setting?

Author information

1
Department of Pediatrics, Division of Infectious Diseases, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA. ptamma1@jhmi.edu

Abstract

We evaluated 222 hospitalized patients whose clinical isolates were tested using standard methods and matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF). MALDI-TOF could have reduced time to appropriate therapy for 28.8% and 44.6% patients based on the treating physician's choices and stewardship team recommendations, respectively. Clinicians should be aware of scenarios in which MALDI-TOF can optimize antibiotic therapy.

PMID:
23917918
DOI:
10.1086/671731
[Indexed for MEDLINE]

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