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Clin Biomech (Bristol, Avon). 1987 Nov;2(4):223-9. doi: 10.1016/0268-0033(87)90086-6.

Experimental models of osteoarthritis: the role of immobilization.

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Institute of Occupational Health, Topeliuksenkatu 41 a A, SF-00250 Helsinki, Finland.


Evidence is reviewed from animal experiments supporting the hypothesis that immobilization, for whatever reason, is one of the pathogenetic factors in musculo-skeletal degeneration. It shows beyond reasonable doubt that immobilization is not only a cause of osteoarthritis but that it delays the healing process.

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