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Otolaryngol Clin North Am. 2013 Aug;46(4):629-43. doi: 10.1016/j.otc.2013.04.004. Epub 2013 Jun 19.

Advances in radiation oncology for the management of oropharyngeal tumors.

Author information

1
Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Unit 97, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

Abstract

The major benefits of modern radiation therapy (eg, intensity-modulated [x-ray] radiation therapy [IMRT]) for oropharyngeal cancer are reduced xerostomia and better quality of life. Intensity-modulated proton therapy may provide additional advantages over IMRT by reducing radiation beam-path toxicities. Several acute and late treatment-related toxicities and symptom constellations must be kept in mind when designing and comparing future treatment strategies, particularly because currently most patients with oropharyngeal carcinoma present with human papillomavirus-positive disease and are expected to have a high probability of long-term survival after treatment.

KEYWORDS:

Head and neck cancer; Intensity-modulated proton therapy; Intensity-modulated radiation therapy; Oropharyngeal tumors; Radiation therapy

PMID:
23910474
DOI:
10.1016/j.otc.2013.04.004
[Indexed for MEDLINE]

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