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Cancer Causes Control. 2013 Nov;24(11):1947-54. doi: 10.1007/s10552-013-0270-5. Epub 2013 Aug 2.

Coffee and tea consumption in relation to prostate cancer prognosis.

Author information

1
Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands, milan.geybels@maastrichtuniversity.nl.

Abstract

BACKGROUND:

Bioactive compounds found in coffee and tea may delay the progression of prostate cancer.

METHODS:

We investigated associations of pre-diagnostic coffee and tea consumption with risk of prostate cancer recurrence/progression. Study participants were men diagnosed with prostate cancer in 2002-2005 in King County, Washington, USA. We assessed the usual pattern of coffee and tea consumption two years before diagnosis date. Prostate cancer-specific outcome events were identified using a detailed follow-up survey. Multivariable Cox proportional hazards regression models were used to estimate hazard ratios (HRs) and 95 % confidence intervals (CIs).

RESULTS:

The analysis of coffee intake in relation to prostate cancer recurrence/progression included 630 patients with a median follow-up of 6.4 years, during which 140 prostate cancer recurrence/progression events were recorded. Approximately 61 % of patients consumed at least one cup of coffee per day. Coffee consumption was associated with a reduced risk of prostate cancer recurrence/progression; the adjusted HR for ≥4 cups/day versus ≤1 cup/week was 0.41 (95 % CI: 0.20, 0.81; p for trend = 0.01). Approximately 14 % of patients consumed one or more cups of tea per day, and tea consumption was unrelated to prostate cancer recurrence/progression.

CONCLUSION:

Results indicate that higher pre-diagnostic coffee consumption is associated with a lower risk of prostate cancer recurrence/progression. This finding will require replication in larger studies.

PMID:
23907772
PMCID:
PMC3859380
DOI:
10.1007/s10552-013-0270-5
[Indexed for MEDLINE]
Free PMC Article

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