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Int J Comput Biol Drug Des. 2013;6(3):255-62. doi: 10.1504/IJCBDD.2013.055460. Epub 2013 Jul 30.

Breast tomosynthesis imaging configuration analysis.

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Department of Electrical and Computer Engineering, Southern Illinois University, Carbondale, IL 62901, USA.


Traditional two-dimensional (2D) X-ray mammography is the most commonly used method for breast cancer diagnosis. Recently, a three-dimensional (3D) Digital Breast Tomosynthesis (DBT) system has been invented, which is likely to challenge the current mammography technology. The DBT system provides stunning 3D information, giving physicians increased detail of anatomical information, while reducing the chance of false negative screening. In this research, two reconstruction algorithms, Back Projection (BP) and Shift-And-Add (SAA), were used to investigate and compare View Angle (VA) and the number of projection images (N) with parallel imaging configurations. In addition, in order to better determine which method displayed better-quality imaging, Modulation Transfer Function (MTF) analyses were conducted with both algorithms, ultimately producing results which improve upon better breast cancer detection. Research studies find evidence that early detection of the disease is the best way to conquer breast cancer, and earlier detection results in the increase of life span for the affected person.

[Indexed for MEDLINE]

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