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Environ Res. 2013 Oct;126:211-4. doi: 10.1016/j.envres.2013.07.002. Epub 2013 Jul 27.

The concentration of bisphenol A in urine is affected by specimen collection, a preservative, and handling.

Author information

1
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NIH/DHHS/USA, PO Box 12233, MD A3-05, NC 27709, USA. Electronic address: Longnec1@niehs.nih.gov.

Abstract

In urine specimens that were collected from pregnant women in a large cohort, 24% contained more than 10 ng/ml of total bisphenol A (BPA), suggesting external contamination. Therefore, we conducted an investigation of the source(s) of extraneous BPA in the specimens. We found that under the conditions used to collect urine specimens in the epidemiologic study, contamination with BPA occurred, and by two separate mechanisms.

KEYWORDS:

BPA; Bisphenol A; Contamination; LOD; LOQ; MoBa; Norwegian Mother and Child Cohort Study; QC; SD; Urine specimen collection; bisphenol A; limit of detection; limit of quantitation; quality control; standard deviation

PMID:
23899777
PMCID:
PMC3805685
DOI:
10.1016/j.envres.2013.07.002
[Indexed for MEDLINE]
Free PMC Article
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