Format

Send to

Choose Destination
See comment in PubMed Commons below
Se Pu. 2013 Apr;31(4):386-91.

[Nano-electrospray ionization-ion mobility spectrometry and its combination with high performance liquid chromatography].

[Article in Chinese]

Author information

1
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.

Abstract

A nano-electrospray ionization-ion mobility spectrometer (nanoESI-IMS) was built up. Firstly, the effects of the parameters such as drift gas flow rate and solvent flow rate on the desolvation capability were studied and optimized. Then, a series of compounds were used to characterize the nanoESI-IMS system. The results showed that, complete desolvation was achieved for nano-electrospray ion droplets with the nanoESI-IMS apparatus. The limit of detection of this instrument for trioctylamine could reach 10 microg/L. Finally, this instrument was coupled to the high performance liquid chromatography (HPLC) as a detector for amines analysis. A test mixture containing triethylamine, diethylamine and butylamine was successfully separated and determined by the HPLC-nanoESI-IMS system. Linear response ranges of about two orders of magnitude were achieved for triethylamine, diethylamine and butylamine with this system.

PMID:
23898640
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center