Format

Send to

Choose Destination
See comment in PubMed Commons below
Am J Infect Control. 2013 Aug;41(8):668-73. doi: 10.1016/j.ajic.2013.01.013.

Modeling the regional spread and control of vancomycin-resistant enterococci.

Author information

1
Public Health Computational and Operations Research, University of Pittsburgh, Pittsburgh, PA 15213, USA. BYL1@pitt.edu

Abstract

BACKGROUND:

Because patients can remain colonized with vancomycin-resistant enterococci (VRE) for long periods of time, VRE may spread from one health care facility to another.

METHODS:

Using the Regional Healthcare Ecosystem Analyst, an agent-based model of patient flow among all Orange County, California, hospitals and communities, we quantified the degree and speed at which changes in VRE colonization prevalence in a hospital may affect prevalence in other Orange County hospitals.

RESULTS:

A sustained 10% increase in VRE colonization prevalence in any 1 hospital caused a 2.8% (none to 62%) average relative increase in VRE prevalence in all other hospitals. Effects took from 1.5 to >10 years to fully manifest. Larger hospitals tended to have greater affect on other hospitals.

CONCLUSIONS:

When monitoring and controlling VRE, decision makers may want to account for regional effects. Knowing a hospital's connections with other health care facilities via patient sharing can help determine which hospitals to include in a surveillance or control program.

KEYWORDS:

Health care-associated infections; Hospitals; Modeling; Simulation; Vancomycin-resistant Enterococcus

PMID:
23896284
PMCID:
PMC3836830
DOI:
10.1016/j.ajic.2013.01.013
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Support Center