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Climacteric. 2014 Apr;17(2):164-72. doi: 10.3109/13697137.2013.828197. Epub 2013 Oct 29.

Effect of menopause on cardiovascular disease and its risk factors: a 9-year follow-up study.

Author information

1
* Reproductive Endocrinology Research Center.

Abstract

OBJECTIVES:

To explore the cardiovascular risk attributable to menopausal status in a 9-year follow-up, population-based study.

METHOD:

All middle-aged women who met our eligibility criteria were selected from the Tehran Lipid and Glucose Study cohort. Data were collected by face-to-face interviews, physical examination and biochemical assessments at 3-year intervals. The World Health Organization classification was used to define menopausal status. Cardiovascular events that occurred in the cohort were investigated by a panel of medical specialists.

RESULTS:

Based on menopausal status, there were no significant differences in cardiovascular disease after adjustment for age, body mass index and other confounders; however, significant relationships between serum concentrations of low density cholesterol and total cholesterol and menopausal status were observed.

CONCLUSIONS:

Menopause, independent of other cardiovascular disease risk factors, incurred cardiometabolic risk.

PMID:
23895384
DOI:
10.3109/13697137.2013.828197
[Indexed for MEDLINE]

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