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Breast Cancer Res Treat. 2013 Aug;140(3):447-52. doi: 10.1007/s10549-013-2643-6. Epub 2013 Jul 28.

Contralateral prophylactic mastectomy in women with breast cancer: trends, predictors, and areas for future research.

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1
Dana-Farber Cancer Institute, Brigham and Women's Hospital, 450 Brookline Ave Boston, Boston, MA 02215, USA.

Abstract

Recent studies have revealed increasing rates of contralateral prophylactic mastectomy (CPM) among women with unilateral early stage breast cancer. This trend has raised concerns, given the lack of evidence for a survival benefit from CPM and the relatively low risk of contralateral breast cancer for most women in this setting. In this article, we review available data regarding the value of CPM, predictors, and outcomes related to CPM, and areas for future research and potential intervention.

PMID:
23893127
PMCID:
PMC3860879
DOI:
10.1007/s10549-013-2643-6
[Indexed for MEDLINE]
Free PMC Article
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