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Nanoscale. 2013 Sep 21;5(18):8340-50. doi: 10.1039/c3nr01990j.

Multiple strategies to activate gold nanoparticles as antibiotics.

Author information

1
CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, 11 Beiyitiao, ZhongGuanCun, 100190, Beijing, China.

Abstract

Widespread antibiotic resistance calls for new strategies. Nanotechnology provides a chance to overcome antibiotic resistance by multiple antibiotic mechanisms. This paper reviews the progress in activating gold nanoparticles with nonantibiotic or antibiotic molecules to combat bacterial resistance, analyzes the gap between experimental achievements and real clinical application, and suggests some potential directions in developing antibacterial nanodrugs.

PMID:
23893008
DOI:
10.1039/c3nr01990j
[Indexed for MEDLINE]
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