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Int J Nanomedicine. 2013;8:2601-11. doi: 10.2147/IJN.S44163. Epub 2013 Jul 19.

Ultra-pure, water-dispersed Au nanoparticles produced by femtosecond laser ablation and fragmentation.

Author information

1
Centre for Micro-Photonics and Industrial Research Institute Swinburne, Faculty of Engineering and Industrial Sciences Swinburne University of Technology, Hawthorn, VIC, Australia.

Abstract

Aqueous solutions of ultra-pure gold nanoparticles have been prepared by methods of femtosecond laser ablation from a solid target and fragmentation from already formed colloids. Despite the absence of protecting ligands, the solutions could be (1) fairly stable and poly size-dispersed; or (2) very stable and monodispersed, for the two fabrication modalities, respectively. Fluorescence quenching behavior and its intricacies were revealed by fluorescence lifetime imaging microscopy in rhodamine 6G water solution. We show that surface-enhanced Raman scattering of rhodamine 6G on gold nanoparticles can be detected with high fidelity down to micromolar concentrations using the nanoparticles. Application potential of pure gold nanoparticles with polydispersed and nearly monodispersed size distributions are discussed.

KEYWORDS:

materials for nanomedicine; methods of nanofabrication and processing; nanotechnologies applications

PMID:
23888114
PMCID:
PMC3722033
DOI:
10.2147/IJN.S44163
[Indexed for MEDLINE]
Free PMC Article
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