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Molecules. 2013 Jul 24;18(8):8752-63. doi: 10.3390/molecules18088752.

Two anti-inflammatory steroidal saponins from Dracaena angustifolia Roxb.

Author information

1
Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung 404, Taiwan.

Abstract

Two new steroidal saponins, named drangustosides A-B (1-2), together with eight known compounds were isolated and characterized from the MeOH extract of Dracaena angustifolia Roxb. The structures of compounds were assigned based on 1D and 2D NMR spectroscopic analyses, including HMQC, HMBC, and NOESY. Compounds 1 and 2 showed anti-inflammatory activity by superoxide generation and elastase release by human neutrophils in response to fMLP/CB.

PMID:
23887717
PMCID:
PMC6270147
DOI:
10.3390/molecules18088752
[Indexed for MEDLINE]
Free PMC Article

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