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Mult Scler. 2014 Apr;20(4):492-5. doi: 10.1177/1352458513496881. Epub 2013 Jul 25.

Evaluation of McDonald MRI criteria for dissemination in space in Korean patients with clinically isolated syndromes.

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1
Department of Neurology, Research Institute and Hospital of National Cancer Center, Korea.

Abstract

We investigated the validity of the 2005 and 2010 McDonald magnetic resonance imaging (MRI) criteria for dissemination in space (DIS) to predict the conversion of clinically definite multiple sclerosis (CDMS) in 94 Korean patients with clinically isolated syndromes (CIS). The sensitivity, specificity, accuracy, positive and negative predictive values of the 2005, 2010 McDonald DIS criteria were comparable to those observed in the Caucasian population. This finding suggests that after careful exclusion of alternative explanations, particularly neuromyelitis optica (NMO) and NMO spectrum disorder (NMOSD), both the 2005 and 2010 McDonald DIS criteria are also useful to predict conversion to CDMS in Korean patients with CIS.

KEYWORDS:

MRI; Multiple sclerosis

PMID:
23886829
DOI:
10.1177/1352458513496881
[Indexed for MEDLINE]
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