Format

Send to

Choose Destination
See comment in PubMed Commons below
Front Oncol. 2013 Jul 17;3:163. doi: 10.3389/fonc.2013.00163. eCollection 2013.

Radiation quality, like art, consists in drawing the line somewhere.

Author information

1
Department of Radiation Oncology, Summa Health System , Akron, OH , USA.

Abstract

The architects of phase I radiochemotherapy development programs impose a semblance of structured radiation "intensity" and adverse event predictability upon radiation-anticancer agent interactions whose natural complexity and improper mixing would otherwise lead to dire health consequences. It is incumbent upon radiation oncology investigators to pledge radiation quality and safety to the participants of radiochemotherapy trials. Measures of radiation quality and safety may be tools to scrutinize radiation-anticancer agent dose and schedule, as well as, radiation field design among diverse radiation delivery platforms. In this article, the merits and demerits of phase I radiochemotherapy quality and safety policies are critiqued considering the current era of rapidly evolving radiation technologies.

KEYWORDS:

radiation quality; radiation safety; radiochemotherapy clinical trial

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Frontiers Media SA Icon for PubMed Central
    Loading ...
    Support Center