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Fertil Steril. 2013 Dec;100(6):e41. doi: 10.1016/j.fertnstert.2013.06.041. Epub 2013 Jul 21.

Uterus transplantation from a deceased donor.

Author information

1
Department of Plastic Surgery, Akdeniz University, Antalya, Turkey. Electronic address: omozkan@hotmail.com.

Abstract

OBJECTIVE:

To demonstrate the technique for uterus retrieval and transplantation from a multiorgan donor.

DESIGN:

Video presentation of our case report. The video uses animation to demonstrate the technique. Institutional Review Board (IRB) approval was obtained.

SETTING:

University hospital.

PATIENT(S):

A 21-year-old woman with complete müllerian agenesis.

INTERVENTION(S):

Uterus allotransplantation has been performed from a deceased donor.

MAIN OUTCOME MEASURE(S):

Acquirement of cyclic menstrual function.

RESULT(S):

This video demonstrates the technique for uterus retrieval, perfusion, and transplantation. The recipient patient has been monitored regularly for vascular flow, immunosuppression, and infection control since the operation.

CONCLUSION(S):

Uterus transplantation requires extensive evaluation of the recipient and donor by an experienced multidisciplinary transplantation team both pre- and postoperatively. It has major risks related to surgery, immunosuppression, and pregnancy. Uterus transplantation might be considered promising only after the birth of a near-term healthy baby.

KEYWORDS:

Uterus transplantation; deceased donor; uterine factor infertility

[Indexed for MEDLINE]

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