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Oral Health Prev Dent. 2013;11(3):251-60. doi: 10.3290/j.ohpd.a30167.

Association of periodontal disease with self-reported systemic disorders in Greece.



The aim of this retrospective investigation was to examine the occurrence of periodontal disease in patients referred to a specialist clinic for neurosurgery and to explore possible associations between common systemic disorders and periodontal disease in an adult population in Greece.


The study sample consisted of 1,652 individuals, 760 males and 892 females, aged 40 to 68 years, with a mean age of 57.3 ± 4.7 years. Data were collected by means of an oral clinical examination and a self-administered questionnaire. Statistical analysis of questionnaire items was performed by using a multiple linear regression analysis model in order to estimate correlations between systemic disorders as independent variables, and the relative frequency of periodontal pockets of 5 mm or more and the frequency of clinical attachment loss of 6 mm or more as dependent variables.


The relative frequencies of periodontal pockets >= 5.0 mm and clinical attachment loss >= 6.0 mm as expressed in terms of mean values were 76% and 70.2%, respectively, for individuals who suffer from cardiovascular disease and 62.3% and 52.9% respectively, for those who suffer from respiratory disease. The depth of periodontal pockets was significantly and positively correlated to the presence of respiratory diseases (P = 0.0001) and diabetes mellitus (P = 0.0001) after adjustment for age, gender and smoking, whereas clinical attachment loss was significantly and positively correlated to the presence of diabetes mellitus (P = 0.0001) and cardiovascular diseases (P = 0.037).


Based on the clinical criteria for established periodontitis, the current study supports associations between periodontal disease and systemic disorders such as diabetes mellitus, cardiovascular and respiratory diseases.

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