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Anaesthesiol Intensive Ther. 2013 Apr-Jun;45(2):85-8. doi: 10.5603/AIT.2013.0019.

Anaesthesia in children with osteogenesis imperfecta - report of 14 general anaesthetics in three children.

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  • 1Department of Anaesthesiology and Intensive Therapy, District Hospital of Orthopaedics and Trauma Surgery in Piekary Śląskie, Poland. oit_urazowy@wp.pl

Abstract

Osteogenesis imperfecta is a rare, genetically inherited syndrome involving connective tissue. It results in extremely fragile bones and disorders of other organs and body systems. Children with osteogenesis imperfecta are susceptible to bone fractures and often require surgery and anaesthesia. We describe a series of 14 general anaesthetics in three patients suffering from this disease. In one of these cases, perioperative hyperthermia was observed. Anaesthetic management of osteogenesis imperfecta and a possible relationship between this syndrome and malignant and non-malignant hyperthermia are discussed.

PMID:
23877901
DOI:
10.5603/AIT.2013.0019
[PubMed - indexed for MEDLINE]
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