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Antimicrob Agents Chemother. 2013 Oct;57(10):5155-7. doi: 10.1128/AAC.01486-13. Epub 2013 Jul 22.

Globally expanding carbapenemase finally appears in Spain: nosocomial outbreak of acinetobacter baumannii producing plasmid-encoded OXA-23 in Barcelona, Spain.

Author information

1
Department of Clinical Microbiology, School of Medicine, IDIBAPS and Barcelona Centre for International Health Research (CRESIB, Hospital Clínic-Universitat de Barcelona), Barcelona, Spain.

Abstract

Resistance of Acinetobacter baumannii clinical isolates to carbapenems is on the rise worldwide mainly in association with the production of OXA-23. Until recently, however, OXA-23 was absent in Spain. In this work, we report the molecular characterization of a hospital outbreak of OXA-23-producing A. baumannii in Barcelona caused by a multidrug-resistant (MDR) clone belonging to international clone IC-II/sequence type ST85 between October 2010 and May 2011. blaOXA-23 was carried in a plasmid of 90 kb and located within the composite transposon Tn2006.

PMID:
23877694
PMCID:
PMC3811394
DOI:
10.1128/AAC.01486-13
[Indexed for MEDLINE]
Free PMC Article

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