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Fibrogenesis Tissue Repair. 2013 Jul 18;6(1):14. doi: 10.1186/1755-1536-6-14.

Non-alcoholic fatty liver disease (NAFLD): a tale of fat and sugar?

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UCL Institute for Liver and Digestive Health, Royal Free Hospital, U3rd Floor, Rowland Hill Street, London NW3 2PF, UK.


The global diffusion of the so-called Western diet, which is enriched in fat and carbohydrates, such as fructose, has been proposed to be an underlying cause of the increased prevalence of metabolic conditions, including non-alcoholic fatty liver disease (NAFLD). This Smart Card summarizes the main metabolic and hepatic histological features of rodent models fed with diets combining high fat and fructose.

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