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Eur J Prev Cardiol. 2014 Dec;21(12):1484-92. doi: 10.1177/2047487313497602. Epub 2013 Jul 17.

The Korean Heart Study: rationale, objectives, protocol, and preliminary results for a new prospective cohort study of 430,920 men and women.

Author information

1
Yonsei University, Seoul, Republic of Korea jsunha@yuhs.ac.
2
University College London, London, UK.
3
Yonsei University, Seoul, Republic of Korea JANGYS1212@yuhs.ac.
4
Korea University, Seoul, Republic of Korea.
5
Seoul National University, Seoul, Republic of Korea.
6
Sungkyunkwan University, Seoul, Republic of Korea.
7
University of Ulsan, Seoul, Republic of Korea.
8
The Catholic University of Korea, Seoul, Republic of Korea.
9
Yonsei University, Seoul, Republic of Korea.
10
Seoul National University, Sungnam, Republic of Korea.
11
CHA University, Sungnam, Republic of Korea.
12
Korea Medical Institute, Seoul, Republic of Korea.
13
Daejeon Sun General Hospital, Daejeon, Republic of Korea.
14
Konyang University Hospital, Daejeon, Republic of Korea.
15
Chungnam National University, Daejeon, Republic of Korea.
16
Soonchunhyang University, Cheonan, Republic of Korea.
17
Daejeon Eulji University Hospital, Daejeon, Republic of Korea.
18
Daegu Catholic Hospital, Daegu, Republic of Korea.
19
Yonsei University, Wonju, Republic of Korea.
20
Ajou University, Suwon, Republic of Korea.
21
University of Ulsan, College of Medicine, Ulsan, Korea.
22
Asan Medical Center, Seoul, Republic of Korea.
23
Dong-A University Medical Center, Busan, Republic of Korea.
24
National Health Insurance Service, Seoul, Republic of Korea.
25
University of Southern California, CA, USA.
26
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Abstract

BACKGROUND:

To describe the rationale, objectives, protocol, and preliminary results for a new prospective cohort study of cardiovascular disease (CVD) risk factors in South Korea.

METHODS:

Study members were recruited from participants in routine health assessments at health promotion centres across South Korea. Established and emerging CVD risk factors were measured. Eighteen centres holding electronic health records agreed to linkage of participants' records to future health insurance claims for monitoring of disease events. The recruitment of 430,920 participants (266,782 men, 164,138 women), aged 30-74 years, provides broad geographical reach across South Korea.

RESULTS:

Risk factor prevalence was more favourable in women than men, and, in general, in the younger rather than older study members. There was also close similarity between the characteristics of the present sample and the Korean National Health and Nutrition Examination Survey. The expected associations between risk factors and both CVD and death were also apparent.

CONCLUSIONS:

Data from the present sample, based on data linkage, show close agreement with South Korea-wide surveys (for risk factor prevalence) and the extant literature (for risk factor associations). These findings gives confidence in future results anticipated from this cohort study of east Asians - a group that has been traditionally under-researched.

KEYWORDS:

Cardiovascular disease; cohort study; prevalence; risk factor

PMID:
23864362
DOI:
10.1177/2047487313497602
[Indexed for MEDLINE]
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