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Gan To Kagaku Ryoho. 2013 Jun;40(6):803-5.

[Two cases of recurrent GIST successfully treated with imatinib mesylate at 100mg/day].

[Article in Japanese]

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Dept. of Surgery, Izumi General Medical Center, Japan.


Case 1: Recurrent tumors from gastric GIST in the liver and the abdominal wall showed partial response with 200mg/day imatinib and maintained partial response at 100mg/day. Case 2: Metastatic liver tumors from the jejunal GIST showed partial response with 200mg/day imatinib. The tumors have been enlarged for interruption of imatinib administration, however, re- treatment with imatinib resulted in partial response again and kept partial response at 100mg/day of imatinib. The two cases seldom encountered adverse events at 100mg/day of imatinib. There are some cases successfully treated with low-dose imatinib mesylate for recurrent GIST.

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