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Gan To Kagaku Ryoho. 2013 Jun;40(6):761-4.

[Usefulness of bevacizumab with paclitaxel for advanced breast cancer - a case report].

[Article in Japanese]

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Dept. of Medical Oncology, Ibaraki Prefectural Central Hospital and Cancer Center, Japan.


A 55-year-old woman with an exudative, necrotizing left breast tumor consulted Ibaraki Prefectural Central Hospital and Cancer Center. We diagnosed her as advanced ER+, PgR-, HER2- invasive ductal carcinoma of the left breast by tumor needle biopsy. FDG-PET/CT revealed multiple lymph node, pulmonary, bone, and hepatic metastases. Systemic chemotherapy with biweekly bevacizumab and weekly paclitaxel(PTX)was administered. The chemotherapy induced a widespread tumor lysis in her left chest wall. We continued chemotherapy, and the ulcer has been healing gradually. We recognized that bevacizumab with PTX successfully brought about a rapid, good local response, and improved the patient's quality of life.

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