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J Comput Assist Tomogr. 2013 Jul-Aug;37(4):602-9. doi: 10.1097/RCT.0b013e318295d0c8.

Computed tomography findings in septic patients with acute respiratory distress syndrome: correlation with survival and pulmonary versus extrapulmonary septic focus.

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1
Klinik für Radiologie, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany. lars.stelter@charite.de

Abstract

OBJECTIVE:

The objective of this study was to evaluate computed tomography (CT) findings in patients with sepsis with unknown inflammatory focus and acute respiratory distress syndrome.

METHODS:

Acute respiratory distress syndrome findings on CT of 36 patients with sepsis were graded on a 6-point scale, and the percentage of affected lung was estimated. Resulting CT scores were correlated to intensive care scores and survival.

RESULTS:

Forty-four percent of the patients died, revealing a significantly higher CT score than survivors (P = 0.01). Survivors showed larger areas of unaffected lung (P < 0.001), whereas patients with fatal outcome had more ground-glass opacities (P = 0.002; sensitivity, 73%; specificity, 57%) and traction bronchiectasis (P = 0.009; sensitivity, 54%; specificity, 68%). Pulmonary findings on CT did not allow discriminating between a pulmonary and extrapulmonary focus. No significant coherence between CT score and intensive care scores could be revealed.

CONCLUSIONS:

A CT scoring system based on pulmonary findings in patients with sepsis with acute respiratory distress syndrome comprises prognostic implications in terms of the patients' survival.

PMID:
23863539
DOI:
10.1097/RCT.0b013e318295d0c8
[Indexed for MEDLINE]
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