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Dermatitis. 2013 Jul-Aug;24(4):176-82. doi: 10.1097/DER.0b013e3182983845.

Patch test reactions associated with sunscreen products and the importance of testing to an expanded series: retrospective analysis of North American Contact Dermatitis Group data, 2001 to 2010.

Author information

1
Department of Dermatology, Veterans Affairs Medical Center, University of Minnesota, Minneapolis, MN 55417, USA. erin.warshaw@va.gov

Abstract

BACKGROUND:

Both active and inactive ingredients in sunscreen may cause contact dermatitis.

OBJECTIVES:

This study aimed to describe allergens associated with a sunscreen source.

METHODS:

A cross-sectional analysis of patients patch tested by the North American Contact Dermatitis Group between 2001 and 2010 was performed.

RESULTS:

Of 23,908 patients patch tested, 219 (0.9%) had sunscreen coded as an allergen source. Patients who were male, with occupational dermatitis, or older (older than 40 years) had significantly lower rates of allergic reactions to sunscreens; the most commonly affected areas were the face and exposed sites (P < 0.0001). The top 3 most frequent allergens in sunscreens were benzophenone-3 (70.2% for 10% concentration, 64.4% for 3% concentration), DL-alpha-tocopherol (4.8%), and fragrance mix I (4.0%). Less than 40% of positive patch test reactions were detected by the North American Contact Dermatitis Group screening series of 65 to 70 allergens.

CONCLUSIONS:

A supplemental antigen series is important in detecting allergy to sunscreens.

PMID:
23857015
DOI:
10.1097/DER.0b013e3182983845
[Indexed for MEDLINE]

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