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Br J Anaesth. 1975 Jan;47(1):79-81.

The effect of intravenous premedication with lorazepam (ativan), pentobarbitone or diazepam on recall.


Sixty-nine patients undergoing regional anaesthesia were premedicated with either lorazepam (1, 2, 3 or 5 mg), diazepam (5 or 10 mg), pentobarbitone (50 mg) or placebo given i.v., on a double-blind, randomized basis. A simple yet rigorous protocol was used to test the effect of these drugs on anterograde recall. Lorazepam 3 and 5 mg was found to affect anterograde recall significantly. None of the other drugs tested affected recall.

[PubMed - indexed for MEDLINE]
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