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Bioinformatics. 2013 Oct 1;29(19):2490-3. doi: 10.1093/bioinformatics/btt407. Epub 2013 Jul 12.

RACER: Rapid and accurate correction of errors in reads.

Author information

1
Department of Computer Science, University of Western Ontario, N6A 5B7 London, ON, Canada.

Abstract

MOTIVATION:

High-throughput next-generation sequencing technologies enable increasingly fast and affordable sequencing of genomes and transcriptomes, with a broad range of applications. The quality of the sequencing data is crucial for all applications. A significant portion of the data produced contains errors, and ever more efficient error correction programs are needed.

RESULTS:

We propose RACER (Rapid and Accurate Correction of Errors in Reads), a new software program for correcting errors in sequencing data. RACER has better error-correcting performance than existing programs, is faster and requires less memory. To support our claims, we performed extensive comparison with the existing leading programs on a variety of real datasets.

AVAILABILITY:

RACER is freely available for non-commercial use at www.csd.uwo.ca/∼ilie/RACER/.

PMID:
23853064
DOI:
10.1093/bioinformatics/btt407
[Indexed for MEDLINE]

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