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Surg Infect (Larchmt). 2013 Aug;14(4):381-4. doi: 10.1089/sur.2012.189. Epub 2013 Jul 12.

Appropriateness of surgical antimicrobial prophylaxis in the Latium region of Italy, 2008: a multicenter study.

Author information

1
Epidemiology Department, National Institute for Infectious Diseases Lazzaro Spallanzani, Rome, Italy. silvia.pittalis@inmi.it

Abstract

BACKGROUND:

There is still wide variability in surgical antimicrobial prophylaxis (SAP) practice by different surgical teams and specialties, with potential impact on adverse events and the emergence of antibiotic resistance.

METHODS:

We assessed SAP appropriateness in a regional prospective multicenter study on the basis of the agreement of the Surgical Care Improvement Project indicators (SCIP-Inf) with Italian guidelines (GL).

RESULTS:

Prophylaxis was administered in 2,664 of 2,835 procedures (94%): In 2,346 of 2,468 (95%) as indicated and in 318 of 367 (86.6%) in which they were not indicated. The SCIP-Inf1 (timing), SCIP-Inf2 (antibiotic choice), and SCIP-Inf3 (duration) were in agreement with GL in 1,172 (50%), 1,983 (84.5%), and 1,121 (48%) of 2,346 procedures, respectively.

CONCLUSIONS:

These results suggest the need for implementation of an antimicrobial stewardship program in this surgical setting.

PMID:
23848414
DOI:
10.1089/sur.2012.189
[Indexed for MEDLINE]

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