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Trends Parasitol. 2013 Aug;29(8):385-93. doi: 10.1016/j.pt.2013.06.003. Epub 2013 Jul 8.

Wolbachia: Can we save lives with a great pandemic?

Author information

1
Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA. daniel.lepage@vanderbilt.edu

Abstract

Wolbachia pipientis is the most common bacterial infection in the animal world and wields a vast influence on invertebrate reproduction, sex determination, speciation, and behavior worldwide. These avenues of research have made seminal gains, including the latest use of Wolbachia to alter mosquito populations and a strengthened focus on using anti-Wolbachia therapies against filarial nematode infections. This work is further bolstered by a more refined knowledge of Wolbachia biology spanning mechanisms to relevance. Here we tally the most up-to-date knowledge in the field and review the immense implications that this global infection has for the basic and applied life sciences.

KEYWORDS:

Wolbachia pipientis; filarial disease; vector control

PMID:
23845310
PMCID:
PMC3775348
DOI:
10.1016/j.pt.2013.06.003
[Indexed for MEDLINE]
Free PMC Article

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