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Anaesthesia. 2013 Sep;68(9):961-5. doi: 10.1111/anae.12251. Epub 2013 Jul 12.

Hypnosis as sole anaesthesia for skin tumour removal in a patient with multiple chemical sensitivity.

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Department of Neurosciences University of Padua, and the Italian Center for Clinical and Experimental Hypnosis, Turin, Italy.


A female patient with multiple chemical sensitivity and previous anaphylactoid reactions to local anaesthetics was admitted for removal of a thigh skin tumour under hypnosis as sole anaesthesia. The hypnotic protocol included hypnotic focused analgesia and a pre-operative pain threshold test. After inducing hypnosis, a wide excision was performed, preserving the deep fascia, and the tumour was removed; the patient's heart rate and blood pressure did not increase during the procedure. When the patient was de-hypnotised, she reported no pain and was discharged immediately. Our case confirms the efficacy of hypnosis and demonstrates that it may be valuable as a sole anaesthetic method in selected cases. Hypnosis can prevent pain perception and surgical stress as a whole, comparing well with anaesthetic drugs.

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